Developmental Vertebrate Physiologist
Assistant Professor of Biology
Education: B.S. 1993, Biology - Oregon State University
M.S. 1995 Biology - Portland State University
Ph.D. 1999 Biology - University of North Texas
Experience:
Assistant Professor of Biology, University of North Dakota
Adjunct Professor Portland State University
Visiting Professor Lewis and Clark College
Visiting Research fellow Linkopings Universitet
Research Focus:
Cardio-Respiratory Physiology
Developmental Physiology of Vertebrates
Reptilian and Avian Biology
My research efforts are concentrated on understanding developmental physiology in vertebrates. The specific areas I study are; the plasticity of developmental cardiovascular physiology in vertebrates, and the differences in cardiovascular maturation between species during embryonic development. These areas are addressed with a variety of approaches and techniques (phylogenetic, pharmacological, environmental, and molecular). In conducting this work, I use a comparative approach, investigating several vertebrate groups including amphibians, reptiles, and birds. Utilizing this method my laboratory seeks to discover the patterns of developmental physiology that unify vertebrates and isolated periods of developmental susceptibility to environmental stress in vertebrates.
Selected Publications :
Crossley II, D.A. and J. Altimiras. 2000. Ontogeny of cholinergic and adrenergic cardiovascular regulation in the domestic chicken ( Gallus gallus). Am. J. Physiol. 279:pp R1091-R1098. Platzack, B., Y. Wang, D. A. Crossley II, V. Lance, J. Hicks and M. Conlon. 2002. Purification, characterization and cardiovascular actions of endothelin-1 and endothelin-3 from the alligator, Alligator mississipiensis. Am. J. Physiol. 282:pp R594-R602. Xu, X., S. E. Meiler, T. P. Zhong, M. Mohideen, D. A. Crossley II, W. W. Burggren and M. C. Fishman. 2002. Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin. Nature Genetics. 30(2):pp 205 - 209.
Burggren, W. W. and D. A. Crossley II. 2002. Comparative cardiovascular development: improving the conceptual framework. Comp Biochem and Physio - Part A: Molecular & Integrative Physiology 132(4):pp 661-674.
Crossley II, D. A., W. W. Burggren and J. Altimiras. 2003. Cardiovascular regulation during hypoxia in embryos of the domestic chicken Gallus gallus. Am. J. Physiol. 284:pp R219-R226.
Burggren, W., D. A. Crossley II, G. Rogowitz and D. Thompson. 2003. Clutch effects explain heart rate variation in embryonic frogs (Cave Coqui, Eleutherodactylus cooki ). Physiol. Biochem. Zool. 76(5):672-678.
Crossley II, D.A., B. P. Bagatto, E. Dzialowski and W. W. Burggren. 2003 Temporal changes in cardiovascular regulation during embryonic development of the Emu ( Dromaius novaehollandiae ). J. Exp. Biol. 206:pp 2895-2902.
Crossley II, D. A., J. W. Hicks and J. Altimiras. 2003. Ontogeny of baroreflex control in the American alligator, Alligator mississippiensis . J. Exp. Biol. 206:pp 2703-2710.
Scanlan T. S., K. L. Suchland, M. E. Hart, Y. Huang, D. A. Crossley II, P. J. Kruzich; J. R. Bunzow, E. T. Lin, D. Hatton, and D. K. Grandy. 2004. 3-Iodothyronamine is an endogenous and rapidly-acting derivative of thyroid hormone. Nature Medicine 10(6): pp 638-642.
Crossley D. A. and J. Altimiras 2005. Cardiovascular development in embryos of the American alligator Alligator mississippiensis : effects of chronic and acute hypoxia J. Exp. Biol. 207:pp31-39. Featured in Inside JEB. |
