My general area interest is organic synthesis, its development and applications in the broadest possible sense. Historically, organic synthesis includes two symbiotic fields - target directed synthesis and synthetic methodology.

In the area of directed synthesis natural compounds are of particular interest as synthetic targets. Natural compounds often possess intricate chemical structure and promising biological activity. Below are some of the natural compounds that are being pursued and evaluated as synthetic targets presently.

REPRESENTATIVE PUBLICATIONS

• Novikov, A.V.; Kennedy, A.R.; Rainier, J.D. "Sulfur Ylide-Initiated Thio-Claisen Rearrangements. The Synthesis of Highly Substituted Indolines," J. Org. Chem. 2003, 68, 993
• Novikov, A.V.; Sabahi, A.; Nyong, A.; Rainier, J.D. "Diastereoselective synthesis of quaternary substituted thioindolines from sulfur ylide intermediates.," Tetrahedron: Asymm. 2003, 14, 911
• Novikov, A.V.; Goldsmith, D.J. "Synthesis of Clerodanes - A Diels-Alder Approach" - in preparation