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Research Development and Compliance

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Institutional Biosafety Manual - December 2005
'

I.

INTRODUCTION

 

A. Scope

 

 

B. Regulatory Forces and Guidlines

 

 

 

C. The Biological Safety Program at UND

 

 

 

 

 1. The Institutional Biosafety Committee (IBC)

 

 
    2. Research Development and Compliance (RD&C)    
    3. Department Chairperson    
    4. Principal Investigator    
    5. Researcher or User    
    6. EHS (Biosafety Officer)    
    7. Employee Health    
    8. Campus Veterinarian    
    9. Other Committees    
         
II. BIOHAZARDS RESEARCH PROJECT REGISTRATION AND APPROVAL    
  A. Introduction    
  B. Registration and Approval Process    
  C. Additional Approvals and Requirements    
    1. Select Biological Agents and Toxins    
    2. Human Blood Tissue    
    3. Biohazards Associated with Animal Handling    
         
III. WORKING SAFELY WITH BIOLOGICAL MATERIALS    
  A. Exposure Control    
    1. Laboratory Practice and Technique    
    2. Safety Equipment (Primary Barriers)    
    3. Facility Design (Secondary Barriers)    
  B. Laboratory Biosafety Levels    
  C. Animal Biosafety Levels    
         
IV. LABORATORY PROCEDURES AND EQUIPMENT    
  A. Guidelines for Good Laboratory Practices at BSL1 and BSL2    
  B. Biological Safety Cabinents (BSC's)    
    1. Types of BSC's    

 

   2. Working in a BSC    
    3. Certification of the BSC    
  C. Decontamination    
    1. Definitions    
    2. When to Decontaminate    
    3. Autoclave Use    
    4. Chemical Disinfectant Use    
  D. Exposure to Infectious Agents    
    1. Intact Skin    
    2. Broken, Cut or Damaged Skin or Puncture Wound    
    3. Eye    
    4. Ingestion of Inhalation    
  E. Biological Material Spills    
    1. Spills and Preparing for Them    
    2. Spills Inside a Biological Safety Cabinent    
    3. Small Spill of Material Outside a Biological Safety Cabinent    
    4. Large Spill of BL2 Material (>500ml) Outside of a Biological Safety Cabinent    
  F. Biological Waste Handling    
    1. Biohazardous Waste (Regulated Medical Waste)    
    2. Animal Bedding Waste    
    3. Animal Carcases    
    4. Animal Waste from BSL2 Animal Room LTL 41    
  G. Packaging and Shipping Biological Materials    
    1. Definitions    
    2. Packaging    
    3. Labeling    
  H. Shipping and Transportation Methods and Requirements    
    1. Registered Mail or the Equivalent    
    2. Federal Express or UPS    
    3. Damaged Packages    
    4. Notice of Delivery    
    5. Importation/Exportation of Etioloigcal Agents    
    6. Other Permits    
         
INDEX    
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Research Development and Compliance
Twamley Hall Room 105
264 Centennial Drive Stop 7134
Grand Forks, ND 58202-7134
Telephone: 701-777-4278
Fax: 701-777-6708
Email: rdc@mail.und.nodak.edu

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