Chemistry Graduate Students' Association - CGSA

                           Meet Richard !


Richard Cochran

Campus address:
University of North Dakota
Chemistry Department
Abbott Hall Room 236
151 Cornell Street Stop 9024
Grand Forks, ND  58202-9024

Advisor: Dr. Alena Kubatova

Research Interest:

My current research is involved with determining efficient and sensitive methods for the extraction and analysis of PAHs and their polar derivatives (including oxy-, nitro-, and hydroxy- species) from atmospheric particulate matter. Determining these analytical methods is a small portion of the overall project focused on polar organic species within particulate matter which are formed through various atmospheric oxidations of volatile organic species (secondary aerosol formation). By determining the gas-particle reaction mechanism that yield these polar species we can then have a greater understanding of how particulate matter effects our climate. Through an analytical approach, I am exploring pressurized fluid extraction (PFE), solid-phase extraction (SPE), and various derivatization compounds by assessing the various thermodynamic impacts on the sensitivity and efficiency of extraction and sample purification. To analyze each sample, gas chromatography-mass spectrometry in selected-ion-total-ion (SITI) acquisition mode utilizing both electron ionization (EI) and negative-ion chemical ionization (NICI) is used.

Cochran, R.; Dongari, N.; Jeong, H.; Beranek, J.; Haddadi, S.; Kubatova, A. Simultaneous determination of polcyclic aromatic hydrocarbons and their oxy-, nitro-, and hydroxy- derivatives. (in progress).

Totslandsdal, A.I.; Herseth, J.I.; Kocbach, A.; Kubatova, A.; Braun, A.; Cochran, R.; Refsnes, M.; Ovrevik, J.; Lag, M. Differential effects of the particle core and organic extract of diesel exhaust particles. European Respiratory Journal. (submitted).

Wu, M.; Audet, A.; Cusic, J.; Seeger, D.; Cochran, R.; Ghribi, O. Broad DNA repair responses in neural injury are associated with activation of the IL-6 pathway in cholesterol-fed rabbits. J. of Neurochemistry, 2009, 111 (4), 1011-1021.